Curation Details
Interaction ID: MINT-7711931

Unique identifier for interactor Auniprotkb:P31947
Unique identifier for interactor Buniprotkb:P04637
Alternative identifier for interactor Aintact:EBI-476295
uniprotkb:Q6FH30
uniprotkb:Q6FH51
uniprotkb:Q96DH0
ensembl:ENSP00000340989.4
intact:EBI-28970316
Alternative identifier for interactor Bintact:EBI-366083
uniprotkb:Q15086
uniprotkb:Q15087
uniprotkb:Q15088
uniprotkb:Q16535
uniprotkb:Q16807
uniprotkb:Q16808
uniprotkb:Q16809
uniprotkb:Q16810
uniprotkb:Q16811
uniprotkb:Q16848
uniprotkb:Q86UG1
uniprotkb:Q8J016
uniprotkb:Q99659
uniprotkb:Q9BTM4
uniprotkb:Q9HAQ8
uniprotkb:Q9NP68
uniprotkb:Q9NPJ2
uniprotkb:Q9NZD0
uniprotkb:Q9UBI2
uniprotkb:Q9UQ61
intact:EBI-28980681
ensembl:ENSP00000269305.4
ensembl:ENSP00000391478.2
ensembl:ENSP00000424104.2
ensembl:ENSP00000426252.2
uniprotkb:Q2XN98
uniprotkb:Q3LRW1
uniprotkb:Q3LRW2
uniprotkb:Q3LRW3
uniprotkb:Q3LRW4
uniprotkb:Q3LRW5
Aliases for Apsi-mi:1433s_human(display_long)
uniprotkb:Stratifin(gene name synonym)
uniprotkb:Epithelial cell marker protein 1(gene name synonym)
uniprotkb:HME1(gene name synonym)
uniprotkb:SFN(gene name)
psi-mi:SFN(display_short)
Aliases for Bpsi-mi:p53_human(display_long)
uniprotkb:TP53(gene name)
psi-mi:TP53(display_short)
uniprotkb:P53(gene name synonym)
uniprotkb:Tumor suppressor p53(gene name synonym)
uniprotkb:Phosphoprotein p53(gene name synonym)
uniprotkb:Antigen NY-CO-13(gene name synonym)
Interaction detection methodspsi-mi:"MI:0065"(isothermal titration calorimetry)
First authorSchumacher et al. (2010)
Identifier of the publicationpubmed:20206173
imex:IM-13635
mint:MINT-7711923
mint:d-09-02281
doi:10.1016/j.febslet.2010.02.065
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7838750
mint:MINT-7711931
imex:IM-13635-1
Confidence scoreintact-miscore:0.74
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1b
comment:homomint
comment:domino
comment:mint
comment:"\"The phosphopeptide(385FKpTEGPDSD393- 7 COOH) of the p53 C-terminus was in vitro synthesized; we have inferred the origin species of p53 phosphopeptide to the human protein, although it corresponds also to the following proteins: p53 from Tupaia glis belangeri (Common tree shrew). p53 from Macaca mulatta (Rhesus macaque). p53 from Macaca fuscata fuscata (Japanese macaque). p53 from Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey). p53 from Cercopithecus aethiops (Green monkey).\""
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:16.3x10^-6(molar)
Creation date2010/02/26
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bphosphorylated residue:387-387(MINT-7711961)
binding-associated region:385-393(MINT-7711938)
Stoichiometry for interactor A2
Stoichiometry for interactor B2
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPeptide synthesis