Unique identifier for interactor A | uniprotkb:P04156 |
Unique identifier for interactor B | uniprotkb:P04156 |
Alternative identifier for interactor A | intact:EBI-977302 uniprotkb:O60489 uniprotkb:P78446 uniprotkb:Q15216 uniprotkb:Q15221 uniprotkb:Q27H91 uniprotkb:Q8TBG0 uniprotkb:Q96E70 uniprotkb:Q9UP19 uniprotkb:Q5QPB4 ensembl:ENSP00000368752.4 ensembl:ENSP00000399376.2 ensembl:ENSP00000411599.2 ensembl:ENSP00000415284.2 |
Alternative identifier for interactor B | intact:EBI-977302 uniprotkb:O60489 uniprotkb:P78446 uniprotkb:Q15216 uniprotkb:Q15221 uniprotkb:Q27H91 uniprotkb:Q8TBG0 uniprotkb:Q96E70 uniprotkb:Q9UP19 uniprotkb:Q5QPB4 ensembl:ENSP00000368752.4 ensembl:ENSP00000399376.2 ensembl:ENSP00000411599.2 ensembl:ENSP00000415284.2 |
Aliases for A | psi-mi:prio_human(display_long) uniprotkb:PrP27-30(gene name synonym) uniprotkb:PrP33-35C(gene name synonym) uniprotkb:ASCR(gene name synonym) uniprotkb:PRNP(gene name) psi-mi:PRNP(display_short) uniprotkb:PRIP(gene name synonym) uniprotkb:PRP(gene name synonym) uniprotkb:ALTPRP(gene name synonym) |
Aliases for B | psi-mi:prio_human(display_long) uniprotkb:PrP27-30(gene name synonym) uniprotkb:PrP33-35C(gene name synonym) uniprotkb:ASCR(gene name synonym) uniprotkb:PRNP(gene name) psi-mi:PRNP(display_short) uniprotkb:PRIP(gene name synonym) uniprotkb:PRP(gene name synonym) uniprotkb:ALTPRP(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0114"(x-ray crystallography) |
First author | Lee et al. (2010) |
Identifier of the publication | pubmed:19927125 imex:IM-15555 mint:MINT-7709859 doi:10.1038/emboj.2009.333 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0407"(direct interaction) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-7610112 mint:MINT-7710174 imex:IM-15555-2 |
Confidence score | intact-miscore:0.97 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Neutral component |
Experimental role B | Neutral component |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | comment:mint comment:"\"mutant hPrPs (residues 90 231) used in this study: F198S/V129 and D178N/V129 (protein with valine polymorphism at residue 129); D178N/M129 and F198S/M129(protein with methionine polymorphism at residue 129).\"" figure legend:f3a; f3b; f3c; f3d; f3e; f3f curation depth:imex curation full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
Parameters of the interaction | - |
Creation date | 2010/02/17 |
Update date | 2024/11/14 |
negative Boolean value | false |
Feature(s) for interactor A | binding-associated region:90-231(MINT-7710177) |
Feature(s) for interactor B | binding-associated region:90-231(MINT-7710177) |
Stoichiometry for interactor A | 4 |
Stoichiometry for interactor B | 0 |
Participant identification method for interactor A | Predetermined participant |
Participant identification method for interactor B | Predetermined participant |