Curation Details
Interaction ID: MINT-7710174

Unique identifier for interactor Auniprotkb:P04156
Unique identifier for interactor Buniprotkb:P04156
Alternative identifier for interactor Aintact:EBI-977302
uniprotkb:O60489
uniprotkb:P78446
uniprotkb:Q15216
uniprotkb:Q15221
uniprotkb:Q27H91
uniprotkb:Q8TBG0
uniprotkb:Q96E70
uniprotkb:Q9UP19
uniprotkb:Q5QPB4
ensembl:ENSP00000368752.4
ensembl:ENSP00000399376.2
ensembl:ENSP00000411599.2
ensembl:ENSP00000415284.2
Alternative identifier for interactor Bintact:EBI-977302
uniprotkb:O60489
uniprotkb:P78446
uniprotkb:Q15216
uniprotkb:Q15221
uniprotkb:Q27H91
uniprotkb:Q8TBG0
uniprotkb:Q96E70
uniprotkb:Q9UP19
uniprotkb:Q5QPB4
ensembl:ENSP00000368752.4
ensembl:ENSP00000399376.2
ensembl:ENSP00000411599.2
ensembl:ENSP00000415284.2
Aliases for Apsi-mi:prio_human(display_long)
uniprotkb:PrP27-30(gene name synonym)
uniprotkb:PrP33-35C(gene name synonym)
uniprotkb:ASCR(gene name synonym)
uniprotkb:PRNP(gene name)
psi-mi:PRNP(display_short)
uniprotkb:PRIP(gene name synonym)
uniprotkb:PRP(gene name synonym)
uniprotkb:ALTPRP(gene name synonym)
Aliases for Bpsi-mi:prio_human(display_long)
uniprotkb:PrP27-30(gene name synonym)
uniprotkb:PrP33-35C(gene name synonym)
uniprotkb:ASCR(gene name synonym)
uniprotkb:PRNP(gene name)
psi-mi:PRNP(display_short)
uniprotkb:PRIP(gene name synonym)
uniprotkb:PRP(gene name synonym)
uniprotkb:ALTPRP(gene name synonym)
Interaction detection methodspsi-mi:"MI:0114"(x-ray crystallography)
First authorLee et al. (2010)
Identifier of the publicationpubmed:19927125
imex:IM-15555
mint:MINT-7709859
doi:10.1038/emboj.2009.333
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7610112
mint:MINT-7710174
imex:IM-15555-2
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:mint
comment:"\"mutant hPrPs (residues 90 231) used in this study: F198S/V129 and D178N/V129 (protein with valine polymorphism at residue 129); D178N/M129 and F198S/M129(protein with methionine polymorphism at residue 129).\""
figure legend:f3a; f3b; f3c; f3d; f3e; f3f
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2010/02/17
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:90-231(MINT-7710177)
Feature(s) for interactor Bbinding-associated region:90-231(MINT-7710177)
Stoichiometry for interactor A4
Stoichiometry for interactor B0
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant