Curation Details
Interaction ID: MINT-74606

Unique identifier for interactor Auniprotkb:P00533
Unique identifier for interactor Buniprotkb:P27986
Alternative identifier for interactor Aintact:EBI-297353
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
Alternative identifier for interactor Bintact:EBI-79464
intact:EBI-28974553
uniprotkb:Q15747
uniprotkb:Q4VBZ7
uniprotkb:Q53EM6
uniprotkb:Q8IXA2
uniprotkb:Q8N1C5
uniprotkb:D3DWA0
uniprotkb:B3KT19
uniprotkb:E7EX19
ensembl:ENSP00000428056.1
ensembl:ENSP00000429277.1
ensembl:ENSP00000513316.1
ensembl:ENSP00000513333.1
Aliases for Apsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Aliases for Bpsi-mi:p85a_human(display_long)
uniprotkb:PIK3R1(gene name)
psi-mi:PIK3R1(display_short)
uniprotkb:GRB1(gene name synonym)
uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)
Interaction detection methodspsi-mi:"MI:0089"(protein array)
First authorJones et al. (2006)
Identifier of the publicationpubmed:16273093
imex:IM-14137
mint:MINT-5218056
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7875969
mint:MINT-74606
imex:IM-14137-81
Confidence scoreintact-miscore:0.81
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST4
kd:295 nanomolar
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/01/13
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Aphosphorylated residue:1016-1016(MINT-1492652)
binding-associated region:1007-1023(MINT-1492650)
Feature(s) for interactor Bbinding-associated region:333-408,624-698(MINT-1492641)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification