Curation Details
Interaction ID: MINT-74590

Unique identifier for interactor Auniprotkb:O43639
Unique identifier for interactor Buniprotkb:P04626
Alternative identifier for interactor Aintact:EBI-713635
uniprotkb:Q9BWN9
uniprotkb:Q9UIC3
uniprotkb:D3DVK1
ensembl:ENSP00000233154.4
ensembl:ENSP00000377018.2
Alternative identifier for interactor Bintact:EBI-641062
uniprotkb:Q14256
uniprotkb:Q6LDV1
uniprotkb:Q9UMK4
uniprotkb:B2RZG3
uniprotkb:B4DHN3
uniprotkb:X5D2V5
ensembl:ENSP00000269571.4
Aliases for Apsi-mi:nck2_human(display_long)
uniprotkb:NCK adaptor protein 2(gene name synonym)
uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)
uniprotkb:NCK2(gene name)
psi-mi:NCK2(display_short)
uniprotkb:GRB4(gene name synonym)
uniprotkb:Growth factor receptor-bound protein 4(gene name synonym)
Aliases for Bpsi-mi:erbb2_human(display_long)
uniprotkb:p185erbB2(gene name synonym)
uniprotkb:MLN19(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)
uniprotkb:Tyrosine kinase-type cell surface receptor HER2(gene name synonym)
uniprotkb:Proto-oncogene Neu(gene name synonym)
uniprotkb:ERBB2(gene name)
psi-mi:ERBB2(display_short)
uniprotkb:HER2(gene name synonym)
uniprotkb:NEU(gene name synonym)
uniprotkb:NGL(gene name synonym)
uniprotkb:Metastatic lymph node gene 19 protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0089"(protein array)
First authorJones et al. (2006)
Identifier of the publicationpubmed:16273093
imex:IM-14137
mint:MINT-5218056
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7881776
mint:MINT-74590
imex:IM-14137-188
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST4
kd:759 nanomolar
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2006/01/13
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:285-359(MINT-1495397)
Feature(s) for interactor Bbinding-associated region:1185-1203(MINT-1495405)
phosphorylated residue:1196-1196(MINT-1495407)
Stoichiometry for interactor A1
Stoichiometry for interactor B1
Participant identification method for interactor ANucleotide sequence identification
Participant identification method for interactor BNucleotide sequence identification