Curation Details
Interaction ID: MINT-7293578

Unique identifier for interactor Auniprotkb:P70335
Unique identifier for interactor Buniprotkb:P61588
Alternative identifier for interactor Aintact:EBI-989293
uniprotkb:Q8C3G4
uniprotkb:Q8C7H0
ensembl:ENSMUSP00000069549.6
Alternative identifier for interactor Bintact:EBI-6930266
uniprotkb:P52199
uniprotkb:Q6ZWS2
ensembl:ENSMUSP00000017288.3
Aliases for Apsi-mi:rock1_mouse(display_long)
uniprotkb:Rho-associated, coiled-coil-containing protein kinase 1(gene name synonym)
uniprotkb:p160 ROCK-1(gene name synonym)
uniprotkb:Rock1(gene name)
psi-mi:Rock1(display_short)
uniprotkb:Rho-associated, coiled-coil-containing protein kinase I(gene name synonym)
Aliases for Bpsi-mi:rnd3_mouse(display_long)
uniprotkb:Rnd3(gene name)
psi-mi:Rnd3(display_short)
uniprotkb:Arhe(gene name synonym)
uniprotkb:Rhoe(gene name synonym)
uniprotkb:Rho family GTPase 3(gene name synonym)
uniprotkb:Rnd3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorKomander et al. (2008)
Identifier of the publicationpubmed:18946488
imex:IM-13799
mint:MINT-7293468
doi:10.1038/emboj.2008.226
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8454517
mint:MINT-7293578
imex:IM-13799-5
Confidence scoreintact-miscore:0.61
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
comment:ROCK1 protein taxid has not been specified
figure legend:F6A
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2009/10/19
Update date2026/01/11
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:?-?(MINT-7293589)
binding-associated region:1-420(MINT-7293591)
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-7293583)
mutation disrupting interaction:173-173(MINT-7293581)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BMolecular weight estimation by coomasie staining