Curation Details
Interaction ID: MINT-7266264

Unique identifier for interactor Auniprotkb:Q00987
Unique identifier for interactor Buniprotkb:P53350
Alternative identifier for interactor Aintact:EBI-389668
intact:EBI-28980679
uniprotkb:A6NL51
uniprotkb:Q13226
uniprotkb:Q13297
uniprotkb:Q13298
uniprotkb:Q13299
uniprotkb:Q13300
uniprotkb:Q13301
uniprotkb:Q53XW0
uniprotkb:Q71TW9
uniprotkb:Q8WYJ1
uniprotkb:Q8WYJ2
uniprotkb:Q9UGI3
uniprotkb:Q9UMT8
uniprotkb:A8K2S6
ensembl:ENSP00000444430.2
Alternative identifier for interactor Bintact:EBI-476768
uniprotkb:Q15153
uniprotkb:Q99746
ensembl:ENSP00000300093.4
Aliases for Apsi-mi:mdm2_human(display_long)
uniprotkb:MDM2(gene name)
psi-mi:MDM2(display_short)
uniprotkb:p53-binding protein Mdm2(gene name synonym)
uniprotkb:Oncoprotein Mdm2(gene name synonym)
uniprotkb:Double minute 2 protein(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase Mdm2(gene name synonym)
Aliases for Bpsi-mi:plk1_human(display_long)
uniprotkb:Polo-like kinase 1(gene name synonym)
uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)
uniprotkb:PLK1(gene name)
psi-mi:PLK1(display_short)
uniprotkb:PLK(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorDias et al. (2009)
Identifier of the publicationpubmed:19833129
imex:IM-13891
mint:MINT-7266226
mint:d-09-01551
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7289106
mint:MINT-7266264
imex:IM-13891-5
Confidence scoreintact-miscore:0.60
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1e
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2009/10/02
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:260-260(MINT-7266293)
binding-associated region:279-491,203-282(MINT-7266273)
glutathione s tranferase tag:?-?(MINT-7266296)
Feature(s) for interactor Bmyc tag:?-?(MINT-7266269)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by autoradiography
Participant identification method for interactor BPredetermined participant