Curation Details
Interaction ID: MINT-7234562

Unique identifier for interactor Auniprotkb:P07384
Unique identifier for interactor Buniprotkb:P04632
Alternative identifier for interactor Aintact:EBI-1542113
uniprotkb:Q2TTR0
uniprotkb:Q6DHV4
ensembl:ENSP00000279247.7
ensembl:ENSP00000431686.1
ensembl:ENSP00000431984.1
ensembl:ENSP00000434176.1
ensembl:ENSP00000435272.1
Alternative identifier for interactor Bintact:EBI-711828
ensembl:ENSP00000246533.2
ensembl:ENSP00000464849.1
uniprotkb:Q8WTX3
uniprotkb:Q96EW0
uniprotkb:A8K0P1
Aliases for Apsi-mi:can1_human(display_long)
uniprotkb:CAPN1(gene name)
psi-mi:CAPN1(display_short)
uniprotkb:CANPL1(gene name synonym)
uniprotkb:Calpain-1 large subunit(gene name synonym)
uniprotkb:Calcium-activated neutral proteinase 1(gene name synonym)
uniprotkb:Calpain mu-type(gene name synonym)
uniprotkb:Micromolar-calpain(gene name synonym)
uniprotkb:Cell proliferation-inducing gene 30 protein(gene name synonym)
uniprotkb:PIG30(orf name)
Aliases for Bpsi-mi:cpns1_human(display_long)
uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)
uniprotkb:Calcium-dependent protease small subunit(gene name synonym)
uniprotkb:Calpain regulatory subunit(gene name synonym)
uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)
uniprotkb:CAPNS1(gene name)
psi-mi:CAPNS1(display_short)
uniprotkb:CAPN4(gene name synonym)
uniprotkb:CAPNS(gene name synonym)
Interaction detection methodspsi-mi:"MI:0435"(protease assay)
First authorTrümpler et al. (2009)
Identifier of the publicationpubmed:19712109
imex:IM-15500
mint:MINT-7234476
doi:10.1111/j.1742-4658.2009.07255
mint:fj-09-0069
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0194"(cleavage reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7187769
mint:MINT-7234562
imex:IM-15500-3
Confidence scoreintact-miscore:0.73
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AEnzyme
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f1c f2c
comment:"\"Authors used micro-calpain from human erythrocytes, which is a heterodimer of calpain-1 (gene name CAPN1, uniprot P07384) and the small regulatory subunit calpain-4 (gene name CAPNS1 (CAPN4) , uniprot P04632).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2009/07/30
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant