| Unique identifier for interactor A | uniprotkb:P62993 |
| Unique identifier for interactor B | uniprotkb:Q07889 |
| Alternative identifier for interactor A | intact:EBI-401755 uniprotkb:P29354 uniprotkb:Q14450 uniprotkb:Q63057 uniprotkb:Q63059 ensembl:ENSP00000339007.4 ensembl:ENSP00000376345.1 ensembl:ENSP00000376347.1 ensembl:ENSP00000496913.1 |
| Alternative identifier for interactor B | intact:EBI-297487 intact:EBI-28968641 uniprotkb:A8K2G3 uniprotkb:B4DXG2 ensembl:ENSP00000384675.2 |
| Aliases for A | psi-mi:grb2_human(display_long) uniprotkb:GRB2(gene name) psi-mi:GRB2(display_short) uniprotkb:ASH(gene name synonym) uniprotkb:Adapter protein GRB2(gene name synonym) uniprotkb:SH2/SH3 adapter GRB2(gene name synonym) uniprotkb:Protein Ash(gene name synonym) |
| Aliases for B | psi-mi:sos1_human(display_long) uniprotkb:SOS1(gene name) psi-mi:SOS1(display_short) |
| Interaction detection methods | psi-mi:"MI:0065"(isothermal titration calorimetry) |
| First author | McDonald et al. (2009) |
| Identifier of the publication | pubmed:19323566 mint:MINT-7215271 doi:10.1021/bi802291y |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-6943438 mint:MINT-7217748 |
| Confidence score | intact-miscore:0.97 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:homomint comment:mint figure legend:f3a t1 t3 f5 curation depth:mimix curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | kd:125.0x10^-6(molar) |
| Creation date | 2009/07/10 |
| Update date | 2024/09/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation decreasing interaction:187-187(MINT-7217754) binding-associated region:159-217(MINT-7217756) mutation decreasing interaction:190-190(MINT-7217752) |
| Feature(s) for interactor B | binding-associated region:1148-1159(MINT-7217761) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |