Curation Details
Interaction ID: MINT-7217731

Unique identifier for interactor Auniprotkb:Q07889
Unique identifier for interactor Buniprotkb:P62993
Alternative identifier for interactor Aintact:EBI-297487
uniprotkb:A8K2G3
uniprotkb:B4DXG2
ensembl:ENSP00000384675.2
intact:EBI-28968641
Alternative identifier for interactor Bintact:EBI-401755
ensembl:ENSP00000339007.4
ensembl:ENSP00000376345.1
ensembl:ENSP00000376347.1
ensembl:ENSP00000496913.1
uniprotkb:P29354
uniprotkb:Q14450
uniprotkb:Q63057
uniprotkb:Q63059
Aliases for Apsi-mi:sos1_human(display_long)
uniprotkb:SOS1(gene name)
psi-mi:SOS1(display_short)
Aliases for Bpsi-mi:grb2_human(display_long)
uniprotkb:GRB2(gene name)
psi-mi:GRB2(display_short)
uniprotkb:ASH(gene name synonym)
uniprotkb:Adapter protein GRB2(gene name synonym)
uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)
uniprotkb:Protein Ash(gene name synonym)
Interaction detection methodspsi-mi:"MI:0065"(isothermal titration calorimetry)
First authorMcDonald et al. (2009)
Identifier of the publicationpubmed:19323566
mint:MINT-7215271
doi:10.1021/bi802291y
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6943402
mint:MINT-7217731
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f2d t1 f5
curation depth:mimix curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:82.0x10^-6(molar)
Creation date2009/07/10
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:1287-1298(MINT-7217740)
Feature(s) for interactor Bbinding-associated region:1-60(MINT-7217735)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant