Curation Details
Interaction ID: MINT-7041474

Unique identifier for interactor Auniprotkb:Q9Y5K6
Unique identifier for interactor Buniprotkb:P22681
Alternative identifier for interactor Aintact:EBI-298152
ensembl:ENSP00000352264.5
uniprotkb:A6NL34
uniprotkb:Q5VYA3
uniprotkb:Q9UG97
Alternative identifier for interactor Bintact:EBI-518228
uniprotkb:A3KMP8
ensembl:ENSP00000264033.3
Aliases for Apsi-mi:cd2ap_human(display_long)
uniprotkb:CD2AP(gene name)
psi-mi:CD2AP(display_short)
uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)
uniprotkb:Adapter protein CMS(gene name synonym)
Aliases for Bpsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorMoncalián et al. (2006)
Identifier of the publicationpubmed:17020880
mint:MINT-7033826
doi:10.1074/jbc.M606411200
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7007069
mint:MINT-7041474
Confidence scoreintact-miscore:0.80
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2e
comment:homomint
comment:domino
comment:mint
comment:The co-precipitation between CMS molecules is a consequence of direct binding of two indipendent CMS molecules to a single c-Cbl molecule
NCBI Taxonomy identifier for the host organismtaxid:9606(human)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2009/05/13
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?(MINT-7041516)
binding-associated region:1-330(MINT-7041485)
Feature(s) for interactor Bmutation decreasing interaction:829-829(MINT-7041535)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant