Curation Details
Interaction ID: MINT-7013831

Unique identifier for interactor Auniprotkb:P0CG48
Unique identifier for interactor Buniprotkb:Q00987
Alternative identifier for interactor Aintact:EBI-3390054
uniprotkb:Q9BWD6
uniprotkb:P02249
uniprotkb:Q8WYN8
uniprotkb:Q91887
uniprotkb:Q9UPK7
uniprotkb:P62988
uniprotkb:P02250
uniprotkb:Q9UEK8
uniprotkb:Q6LDU5
uniprotkb:Q91888
uniprotkb:Q6LBL4
uniprotkb:Q9UEF2
uniprotkb:Q29120
uniprotkb:P02248
uniprotkb:Q9BX98
uniprotkb:Q9UEG1
ensembl:ENSP00000344818.5
ensembl:ENSP00000441543.1
Alternative identifier for interactor Bintact:EBI-389668
intact:EBI-28980679
uniprotkb:A6NL51
uniprotkb:Q13226
uniprotkb:Q13297
uniprotkb:Q13298
uniprotkb:Q13299
uniprotkb:Q13300
uniprotkb:Q13301
uniprotkb:Q53XW0
uniprotkb:Q71TW9
uniprotkb:Q8WYJ1
uniprotkb:Q8WYJ2
uniprotkb:Q9UGI3
uniprotkb:Q9UMT8
uniprotkb:A8K2S6
ensembl:ENSP00000444430.2
Aliases for Apsi-mi:ubc_human(display_long)
uniprotkb:UBC(gene name)
psi-mi:UBC(display_short)
Aliases for Bpsi-mi:mdm2_human(display_long)
uniprotkb:MDM2(gene name)
psi-mi:MDM2(display_short)
uniprotkb:p53-binding protein Mdm2(gene name synonym)
uniprotkb:Oncoprotein Mdm2(gene name synonym)
uniprotkb:Double minute 2 protein(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase Mdm2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorChen et al. (2009)
Identifier of the publicationmint:MINT-7013664
pubmed:19098711
imex:IM-11688
doi:10.1038/embor.2008.231
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8529739
mint:MINT-7013831
imex:IM-11688-2
Confidence scoreintact-miscore:0.82
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3D
comment:homomint
comment:mint
comment:Interaction occurs only if p53 is also overexpressed and increases when RYBP is overexpressed.
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-a_549)
taxid:9606(Homo sapiens A549 lung carcinoma cell)
Parameters of the interaction-
Creation date2009/03/18
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?(MINT-7013834)
Feature(s) for interactor Bt7 tag:?-?(MINT-7013838)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BWestern blot