Curation Details
Interaction ID: MINT-68707

Unique identifier for interactor Auniprotkb:P35568
Unique identifier for interactor Buniprotkb:P42336
Alternative identifier for interactor Aintact:EBI-517592
ensembl:ENSP00000304895.4
intact:EBI-28983786
Alternative identifier for interactor Bintact:EBI-2116585
uniprotkb:Q14CW1
uniprotkb:Q99762
ensembl:ENSP00000263967.3
Aliases for Apsi-mi:irs1_human(display_long)
uniprotkb:IRS1(gene name)
psi-mi:IRS1(display_short)
Aliases for Bpsi-mi:pk3ca_human(display_long)
uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)
uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)
uniprotkb:PIK3CA(gene name)
psi-mi:PIK3CA(display_short)
uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)
uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorMorrow et al. (2005)
Identifier of the publicationpubmed:16150444
imex:IM-11186
mint:MINT-5217942
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7813120
mint:MINT-68707
imex:IM-11186-1
Confidence scoreintact-miscore:0.85
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2D
comment:interaction verified in a panel of human colorectal cancer cell lines
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-4(in vivo)
taxid:-4(in vivo)
Parameters of the interaction-
Creation date2005/10/31
Update date2024/09/10
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot