Curation Details
Interaction ID: MINT-6823537

Unique identifier for interactor Auniprotkb:P31749
Unique identifier for interactor Buniprotkb:Q00987
Alternative identifier for interactor Aintact:EBI-296087
uniprotkb:Q9BWB6
uniprotkb:B2RAM5
ensembl:ENSP00000270202.4
ensembl:ENSP00000384293.2
ensembl:ENSP00000385326.2
ensembl:ENSP00000450688.1
ensembl:ENSP00000451166.1
ensembl:ENSP00000451828.1
ensembl:ENSP00000497822.1
ensembl:ENSP00000507879.1
uniprotkb:B7Z5R1
Alternative identifier for interactor Bintact:EBI-389668
intact:EBI-28980679
uniprotkb:A6NL51
uniprotkb:Q13226
uniprotkb:Q13297
uniprotkb:Q13298
uniprotkb:Q13299
uniprotkb:Q13300
uniprotkb:Q13301
uniprotkb:Q53XW0
uniprotkb:Q71TW9
uniprotkb:Q8WYJ1
uniprotkb:Q8WYJ2
uniprotkb:Q9UGI3
uniprotkb:Q9UMT8
uniprotkb:A8K2S6
ensembl:ENSP00000444430.2
Aliases for Apsi-mi:akt1_human(display_long)
uniprotkb:AKT1(gene name)
psi-mi:AKT1(display_short)
uniprotkb:PKB(gene name synonym)
uniprotkb:RAC(gene name synonym)
uniprotkb:RAC-PK-alpha(gene name synonym)
uniprotkb:Protein kinase B(gene name synonym)
uniprotkb:Proto-oncogene c-Akt(gene name synonym)
uniprotkb:Protein kinase B alpha(gene name synonym)
Aliases for Bpsi-mi:mdm2_human(display_long)
uniprotkb:MDM2(gene name)
psi-mi:MDM2(display_short)
uniprotkb:p53-binding protein Mdm2(gene name synonym)
uniprotkb:Oncoprotein Mdm2(gene name synonym)
uniprotkb:Double minute 2 protein(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase Mdm2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorWood et al. (2009)
Identifier of the publicationmint:MINT-6823529
pubmed:19166854
imex:IM-11640
mint:d-08-01901
doi:10.1016/j.febslet.2009.01.003
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8554425
mint:MINT-6823537
imex:IM-11640-2
Confidence scoreintact-miscore:0.81
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2A F3
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2009/01/12
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:118-480(MINT-6823543)
mutation increasing interaction:473-473(MINT-6823545)
Feature(s) for interactor Bphosphorylated residue:188-188(MINT-6823552)
phosphorylated residue:166-166(MINT-6823550)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant