Curation Details
Interaction ID: MINT-6805510

Unique identifier for interactor Auniprotkb:O60934
Unique identifier for interactor Buniprotkb:Q14676
Alternative identifier for interactor Aintact:EBI-494844
uniprotkb:B2R626
uniprotkb:B2RNC5
ensembl:ENSP00000265433.4
ensembl:ENSP00000513229.1
ensembl:ENSP00000513245.1
uniprotkb:O60672
uniprotkb:Q32NF7
uniprotkb:Q53FM6
uniprotkb:Q63HR6
uniprotkb:Q7LDM2
Alternative identifier for interactor Bintact:EBI-495644
ensembl:ENSP00000365588.3
ensembl:ENSP00000373060.4
ensembl:ENSP00000387429.2
ensembl:ENSP00000396484.2
ensembl:ENSP00000404318.2
ensembl:ENSP00000409167.2
ensembl:ENSP00000415212.2
ensembl:ENSP00000416511.2
intact:EBI-28978228
uniprotkb:A2AB04
uniprotkb:A2BF04
uniprotkb:A2RRA8
uniprotkb:A7YY86
uniprotkb:B0S8A2
uniprotkb:Q0EFC2
uniprotkb:Q2L6H7
uniprotkb:Q2TAZ4
uniprotkb:Q5ST83
uniprotkb:Q68CQ3
uniprotkb:Q86Z06
uniprotkb:Q96QC2
uniprotkb:Q5JP55
uniprotkb:Q5JP56
Aliases for Apsi-mi:nbn_human(display_long)
uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)
uniprotkb:Cell cycle regulatory protein p95(gene name synonym)
uniprotkb:NBN(gene name)
psi-mi:NBN(display_short)
uniprotkb:NBS1(gene name synonym)
uniprotkb:NBS(gene name synonym)
uniprotkb:P95(gene name synonym)
Aliases for Bpsi-mi:mdc1_human(display_long)
uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)
uniprotkb:MDC1(gene name)
psi-mi:MDC1(display_short)
uniprotkb:KIAA0170(gene name synonym)
uniprotkb:NFBD1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorChapman et al. (2008)
Identifier of the publicationpubmed:18583988
imex:IM-9695
mint:MINT-6805208
doi:10.1038/embor.2008.103
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7990206
mint:MINT-6805510
imex:IM-9695-3
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3b
comment:homomint
comment:Only if MDC1 is phosphorylated by CK2.
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/12/17
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:160-160(MINT-6805521)
binding-associated region:1-348(MINT-6805519)
Feature(s) for interactor Bbinding-associated region:181-517(MINT-6805513)
glutathione s tranferase tag:?-?(MINT-6805515)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BAnti tag western blot