Curation Details
Interaction ID: MINT-6805435

Unique identifier for interactor Auniprotkb:Q14676
Unique identifier for interactor Buniprotkb:O60934
Alternative identifier for interactor Aintact:EBI-495644
uniprotkb:A2AB04
uniprotkb:A2BF04
uniprotkb:A2RRA8
uniprotkb:A7YY86
uniprotkb:B0S8A2
uniprotkb:Q0EFC2
uniprotkb:Q2L6H7
uniprotkb:Q2TAZ4
uniprotkb:Q5ST83
uniprotkb:Q68CQ3
uniprotkb:Q86Z06
uniprotkb:Q96QC2
uniprotkb:Q5JP55
uniprotkb:Q5JP56
ensembl:ENSP00000365588.3
ensembl:ENSP00000373060.4
ensembl:ENSP00000387429.2
ensembl:ENSP00000396484.2
ensembl:ENSP00000404318.2
ensembl:ENSP00000409167.2
ensembl:ENSP00000415212.2
ensembl:ENSP00000416511.2
intact:EBI-28978228
Alternative identifier for interactor Bintact:EBI-494844
uniprotkb:O60672
uniprotkb:Q32NF7
uniprotkb:Q53FM6
uniprotkb:Q63HR6
uniprotkb:Q7LDM2
uniprotkb:B2R626
uniprotkb:B2RNC5
ensembl:ENSP00000265433.4
ensembl:ENSP00000513229.1
ensembl:ENSP00000513245.1
Aliases for Apsi-mi:mdc1_human(display_long)
uniprotkb:Nuclear factor with BRCT domains 1(gene name synonym)
uniprotkb:MDC1(gene name)
psi-mi:MDC1(display_short)
uniprotkb:KIAA0170(gene name synonym)
uniprotkb:NFBD1(gene name synonym)
Aliases for Bpsi-mi:nbn_human(display_long)
uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)
uniprotkb:Cell cycle regulatory protein p95(gene name synonym)
uniprotkb:NBN(gene name)
psi-mi:NBN(display_short)
uniprotkb:NBS1(gene name synonym)
uniprotkb:NBS(gene name synonym)
uniprotkb:P95(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorChapman et al. (2008)
Identifier of the publicationpubmed:18583988
imex:IM-9695
mint:MINT-6805208
doi:10.1038/embor.2008.103
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7991113
mint:MINT-6805435
imex:IM-9695-10
Confidence scoreintact-miscore:0.97
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2E
comment:homomint
comment:CK2 inhibitor treatment destroys the interaction.
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-u2os)
taxid:9606(Homo sapiens U2OS osteosarcoma cell)
Parameters of the interaction-
Creation date2008/12/17
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Aha tag:?-?(MINT-6805457)
binding-associated region:181-517(MINT-6805438)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BWestern blot