Curation Details
Interaction ID: MINT-6799829

Unique identifier for interactor Auniprotkb:P29350
Unique identifier for interactor Buniprotkb:P08922
Alternative identifier for interactor Aintact:EBI-78260
uniprotkb:A8K306
uniprotkb:G3V0F8
uniprotkb:Q9UK67
ensembl:ENSP00000326010.9
intact:EBI-28977917
uniprotkb:Q969V8
Alternative identifier for interactor Bintact:EBI-7371065
ensembl:ENSP00000357494.3
uniprotkb:Q5TDB5
uniprotkb:Q15368
intact:MINT-2800684
Aliases for Apsi-mi:ptn6_human(display_long)
uniprotkb:PTPN6(gene name)
psi-mi:PTPN6(display_short)
uniprotkb:HCP(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)
uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)
uniprotkb:SH-PTP1(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)
uniprotkb:PTP1C(gene name synonym)
Aliases for Bpsi-mi:ros1_human(display_long)
uniprotkb:ROS1(gene name)
psi-mi:ROS1(display_short)
uniprotkb:MCF3(gene name synonym)
uniprotkb:Proto-oncogene c-Ros(gene name synonym)
uniprotkb:Proto-oncogene c-Ros-1(gene name synonym)
uniprotkb:ROS(gene name synonym)
uniprotkb:c-Ros receptor tyrosine kinase(gene name synonym)
uniprotkb:Receptor tyrosine kinase c-ros oncogene 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorTeichmann et al. (2007)
Identifier of the publicationpubmed:17416557
mint:MINT-6788191
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7371270
mint:MINT-6799829
Confidence scoreintact-miscore:0.64
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Table 3
kinetics:kd 2.2 millimolar
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/11/13
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:?-?(MINT-6799832)
glutathione s tranferase tag:?-?(MINT-6799835)
Feature(s) for interactor Bphosphorylated residue:2110-2110(MINT-6799841)
binding-associated region:2106-2121(MINT-6799839)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPeptide synthesis