Curation Details
Interaction ID: MINT-6799814

Unique identifier for interactor Auniprotkb:P08922
Unique identifier for interactor Buniprotkb:P18031
Alternative identifier for interactor Aintact:EBI-7371065
ensembl:ENSP00000357494.3
uniprotkb:Q5TDB5
uniprotkb:Q15368
intact:MINT-2800684
Alternative identifier for interactor Bintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Aliases for Apsi-mi:ros1_human(display_long)
uniprotkb:ROS1(gene name)
psi-mi:ROS1(display_short)
uniprotkb:MCF3(gene name synonym)
uniprotkb:Proto-oncogene c-Ros(gene name synonym)
uniprotkb:Proto-oncogene c-Ros-1(gene name synonym)
uniprotkb:ROS(gene name synonym)
uniprotkb:c-Ros receptor tyrosine kinase(gene name synonym)
uniprotkb:Receptor tyrosine kinase c-ros oncogene 1(gene name synonym)
Aliases for Bpsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorTeichmann et al. (2007)
Identifier of the publicationpubmed:17416557
mint:MINT-6788191
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7371193
mint:MINT-6799814
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Table 3
kinetics:kd 4.5 millimolar
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/11/13
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:2106-2121(MINT-6799826)
phosphorylated residue:2115-2115(MINT-6799824)
Feature(s) for interactor Bbinding-associated region:?-?(MINT-6799817)
glutathione s tranferase tag:?-?(MINT-6799820)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APeptide synthesis
Participant identification method for interactor BPredetermined participant