| Unique identifier for interactor A | uniprotkb:P35570 |
| Unique identifier for interactor B | uniprotkb:P06213 |
| Alternative identifier for interactor A | intact:EBI-520230 |
| Alternative identifier for interactor B | intact:EBI-475899 uniprotkb:Q17RW0 uniprotkb:Q59H98 uniprotkb:Q9UCB7 uniprotkb:Q9UCB8 uniprotkb:Q9UCB9 ensembl:ENSP00000303830.4 |
| Aliases for A | psi-mi:irs1_rat(display_long) uniprotkb:pp185(gene name synonym) uniprotkb:Irs1(gene name) psi-mi:Irs1(display_short) uniprotkb:Irs-1(gene name synonym) |
| Aliases for B | psi-mi:insr_human(display_long) uniprotkb:INSR(gene name) psi-mi:INSR(display_short) |
| Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
| First author | Picha et al. (2007) |
| Identifier of the publication | pubmed:17135270 mint:MINT-6741609 |
| NCBI Taxonomy identifier for interactor A | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7138514 mint:MINT-6795115 |
| Confidence score | intact-miscore:0.79 |
| Complex expansion | - |
| Biological role A | Enzyme target |
| Biological role B | Enzyme |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:T1 comment:the full length enzyme is more active versus the IRS1 peptide comment:homomint comment:mint partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | kcat:18.4x10(second) km:19.1x10^-6(molar) |
| Creation date | 2008/10/23 |
| Update date | 2025/03/31 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:624-635(MINT-6795119) |
| Feature(s) for interactor B | glutathione s tranferase tag:?-?(MINT-6795128) binding-associated region:?-?(MINT-6795125) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Peptide synthesis |
| Participant identification method for interactor B | Predetermined participant |