Unique identifier for interactor A | uniprotkb:P18031 |
Unique identifier for interactor B | uniprotkb:P19235 |
Alternative identifier for interactor A | intact:EBI-968788 uniprotkb:Q5TGD8 uniprotkb:Q9BQV9 uniprotkb:Q9NQQ4 ensembl:ENSP00000360683.3 |
Alternative identifier for interactor B | intact:EBI-617321 ensembl:ENSP00000222139.5 uniprotkb:Q15443 uniprotkb:Q2M205 uniprotkb:B2RCG4 |
Aliases for A | psi-mi:ptn1_human(display_long) uniprotkb:PTPN1(gene name) psi-mi:PTPN1(display_short) uniprotkb:PTP1B(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) |
Aliases for B | psi-mi:epor_human(display_long) uniprotkb:EPOR(gene name) psi-mi:EPOR(display_short) |
Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
First author | Cohen et al. (2004) |
Identifier of the publication | pubmed:14527337 mint:MINT-6671811 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-7039404 mint:MINT-6794748 |
Confidence score | intact-miscore:0.60 |
Complex expansion | - |
Biological role A | Enzyme |
Biological role B | Enzyme target |
Experimental role A | Neutral component |
Experimental role B | Neutral component |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:F8 comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein. comment:WT and D\A Trapping mutant form of PTP1B. comment:homomint comment:mint partial coverage:partial coverage |
NCBI Taxonomy identifier for the host organism | taxid:10090(mouse-ba_f3) taxid:10090(Mouse pro B cells IL-3 dependent) |
Parameters of the interaction | - |
Creation date | 2008/10/23 |
Update date | 2025/03/31 |
negative Boolean value | false |
Feature(s) for interactor A | glutathione s tranferase tag:?-?(MINT-6794752) |
Feature(s) for interactor B | - |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Predetermined participant |
Participant identification method for interactor B | Western blot |