Curation Details
Interaction ID: MINT-6794748

Unique identifier for interactor Auniprotkb:P19235
Unique identifier for interactor Buniprotkb:P18031
Alternative identifier for interactor Aintact:EBI-617321
uniprotkb:B2RCG4
ensembl:ENSP00000222139.5
uniprotkb:Q15443
uniprotkb:Q2M205
Alternative identifier for interactor Bintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Aliases for Apsi-mi:epor_human(display_long)
uniprotkb:EPOR(gene name)
psi-mi:EPOR(display_short)
Aliases for Bpsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorCohen et al. (2004)
Identifier of the publicationpubmed:14527337
mint:MINT-6671811
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7039404
mint:MINT-6794748
Confidence scoreintact-miscore:0.60
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F8
comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein.
comment:WT and D\A Trapping mutant form of PTP1B.
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:10090(mouse-ba_f3)
taxid:10090(Mouse pro B cells IL-3 dependent)
Parameters of the interaction-
Creation date2008/10/23
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-6794752)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BPredetermined participant