Curation Details
Interaction ID: MINT-6794107

Unique identifier for interactor Auniprotkb:P35570
Unique identifier for interactor Buniprotkb:Q63787
Alternative identifier for interactor Aintact:EBI-520230
Alternative identifier for interactor Bintact:EBI-518443
uniprotkb:O55085
uniprotkb:P70544
uniprotkb:Q63790
Aliases for Apsi-mi:irs1_rat(display_long)
uniprotkb:pp185(gene name synonym)
uniprotkb:Irs1(gene name)
psi-mi:Irs1(display_short)
uniprotkb:Irs-1(gene name synonym)
Aliases for Bpsi-mi:p85a_rat(display_long)
uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)
uniprotkb:Pik3r1(gene name)
psi-mi:Pik3r1(display_short)
Interaction detection methodspsi-mi:"MI:0019"(coimmunoprecipitation)
First authorShimizu et al. (2002)
Identifier of the publicationmint:MINT-6741604
pubmed:12446583
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8561932
mint:MINT-6794107
Confidence scoreintact-miscore:0.59
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2B
comment:The PTP1B overexpression disrupts the interaction
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:10116(rat-l6)
taxid:10116(Rattus norvegicus)
Parameters of the interaction-
Creation date2008/10/23
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot