| Unique identifier for interactor A | uniprotkb:P06213 |
| Unique identifier for interactor B | uniprotkb:P35569 |
| Alternative identifier for interactor A | intact:EBI-475899 uniprotkb:Q17RW0 uniprotkb:Q59H98 uniprotkb:Q9UCB7 uniprotkb:Q9UCB8 uniprotkb:Q9UCB9 ensembl:ENSP00000303830.4 |
| Alternative identifier for interactor B | intact:EBI-400825 |
| Aliases for A | psi-mi:insr_human(display_long) uniprotkb:INSR(gene name) psi-mi:INSR(display_short) |
| Aliases for B | psi-mi:irs1_mouse(display_long) uniprotkb:Irs1(gene name) psi-mi:Irs1(display_short) uniprotkb:Irs-1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
| First author | Shimizu et al. (2002) |
| Identifier of the publication | mint:MINT-6741604 pubmed:12446583 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8561837 mint:MINT-6794075 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F2A comment:The phosphatase overexpression cause the dephosphorylation of predicted substrate. comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein. comment:mint dataset:Virus - Publications including interactions involving viral proteins |
| NCBI Taxonomy identifier for the host organism | taxid:10090(mouse-3t3_l1) taxid:10090(Mus musculus embryonic cells Fibroblast-like. Adipose like when confluent) |
| Parameters of the interaction | - |
| Creation date | 2008/10/23 |
| Update date | 2024/09/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | tag:?-?(MINT-6794086) binding-associated region:?-?(MINT-6794082) mutation disrupting interaction:215-215(MINT-6794084) |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Western blot |