Curation Details
Interaction ID: MINT-6793745

Unique identifier for interactor Auniprotkb:P18031
Unique identifier for interactor Buniprotkb:P35568
Alternative identifier for interactor Aintact:EBI-968788
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
ensembl:ENSP00000360683.3
Alternative identifier for interactor Bintact:EBI-517592
ensembl:ENSP00000304895.4
intact:EBI-28983786
Aliases for Apsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Aliases for Bpsi-mi:irs1_human(display_long)
uniprotkb:IRS1(gene name)
psi-mi:IRS1(display_short)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorRavichandran et al. (2001)
Identifier of the publicationpubmed:11579209
mint:MINT-6732079
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7985002
mint:MINT-6793745
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F8
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:9534(chlae-cos_7)
taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)
Parameters of the interaction-
Creation date2008/10/23
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:?-?(MINT-6793752)
mutation decreasing interaction:50-50(MINT-6793754)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot