Curation Details
Interaction ID: MINT-6793586

Unique identifier for interactor Auniprotkb:P18031
Unique identifier for interactor Buniprotkb:P06213
Alternative identifier for interactor Aintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Alternative identifier for interactor Bintact:EBI-475899
uniprotkb:Q17RW0
uniprotkb:Q59H98
uniprotkb:Q9UCB7
uniprotkb:Q9UCB8
uniprotkb:Q9UCB9
ensembl:ENSP00000303830.4
Aliases for Apsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Aliases for Bpsi-mi:insr_human(display_long)
uniprotkb:INSR(gene name)
psi-mi:INSR(display_short)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorSalmeen et al. (2000)
Identifier of the publicationpubmed:11163213
mint:MINT-6672135
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7483780
mint:MINT-6793586
Confidence scoreintact-miscore:0.98
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionic50:14.0x10^-6(molar)
km:100.0x10^-6(molar)
Creation date2008/10/23
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?(MINT-6793599)
binding-associated region:?-?(MINT-6793597)
Feature(s) for interactor Bphosphorylated residue:1190-1190(MINT-6793592)
binding-associated region:1182-1192(MINT-6793590)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPeptide synthesis