| Unique identifier for interactor A | uniprotkb:P06213 |
| Unique identifier for interactor B | uniprotkb:P18031 |
| Alternative identifier for interactor A | intact:EBI-475899 uniprotkb:Q17RW0 uniprotkb:Q59H98 uniprotkb:Q9UCB7 uniprotkb:Q9UCB8 uniprotkb:Q9UCB9 ensembl:ENSP00000303830.4 |
| Alternative identifier for interactor B | intact:EBI-968788 uniprotkb:Q5TGD8 uniprotkb:Q9BQV9 uniprotkb:Q9NQQ4 ensembl:ENSP00000360683.3 |
| Aliases for A | psi-mi:insr_human(display_long) uniprotkb:INSR(gene name) psi-mi:INSR(display_short) |
| Aliases for B | psi-mi:ptn1_human(display_long) uniprotkb:PTPN1(gene name) psi-mi:PTPN1(display_short) uniprotkb:PTP1B(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
| First author | Salmeen et al. (2000) |
| Identifier of the publication | pubmed:11163213 mint:MINT-6672135 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7483690 mint:MINT-6793552 |
| Confidence score | intact-miscore:0.98 |
| Complex expansion | - |
| Biological role A | Enzyme target |
| Biological role B | Enzyme |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F1 comment:homomint comment:mint partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | ic50:14.0x10^-6(molar) km:100.0x10^-6(molar) |
| Creation date | 2008/10/23 |
| Update date | 2024/09/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | phosphorylated residue:1185-1185(MINT-6793567) binding-associated region:1182-1192(MINT-6793565) |
| Feature(s) for interactor B | glutathione s tranferase tag:?-?(MINT-6793558) binding-associated region:?-?(MINT-6793556) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Peptide synthesis |
| Participant identification method for interactor B | Predetermined participant |