Curation Details
Interaction ID: MINT-6793439

Unique identifier for interactor Auniprotkb:P35569
Unique identifier for interactor Buniprotkb:P18031
Alternative identifier for interactor Aintact:EBI-400825
Alternative identifier for interactor Bintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Aliases for Apsi-mi:irs1_mouse(display_long)
uniprotkb:Irs1(gene name)
psi-mi:Irs1(display_short)
uniprotkb:Irs-1(gene name synonym)
Aliases for Bpsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorVenable et al. (2000)
Identifier of the publicationpubmed:10751417
mint:MINT-6741599
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7258566
mint:MINT-6793439
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3
comment:The phosphatase overexpression cause the dephosphorylation of predicted substrate.
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:10090(mouse-3t3_l1)
taxid:10090(Mus musculus embryonic cells Fibroblast-like. Adipose like when confluent)
Parameters of the interaction-
Creation date2008/10/23
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:?-?(MINT-6793443)
tag:?-?(MINT-6793445)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BPredetermined participant