Curation Details
Interaction ID: MINT-6793284

Unique identifier for interactor Auniprotkb:P00533
Unique identifier for interactor Buniprotkb:P20417
Alternative identifier for interactor Aintact:EBI-297353
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
Alternative identifier for interactor Bintact:EBI-916819
ensembl:ENSRNOP00000014309.2
ensembl:ENSRNOP00055005751
ensembl:ENSRNOP00060000740
ensembl:ENSRNOP00065016650
Aliases for Apsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Aliases for Bpsi-mi:ptn1_rat(display_long)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
uniprotkb:Ptpn1(gene name)
psi-mi:Ptpn1(display_short)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorZhang et al. (1993)
Identifier of the publicationmint:MINT-6732123
pubmed:7685104
doi:10.1073/pnas.90.10.4446
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8605454
mint:MINT-6793284
Confidence scoreintact-miscore:0.80
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:T2
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkcat:54.8x10(second)
km:1.24x10^-6(molar)
Creation date2008/10/23
Update date2024/09/11
negative Boolean valuefalse
Feature(s) for interactor Aphosphorylated residue:1016-1016(MINT-6800844)
mutation decreasing interaction:1014-1014(MINT-6800846)
binding-associated region:1011-1021(MINT-6793288)
Feature(s) for interactor Bbinding-associated region:?-?(MINT-6939665)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APeptide synthesis
Participant identification method for interactor BPredetermined participant