Unique identifier for interactor A | uniprotkb:P20417 |
Unique identifier for interactor B | uniprotkb:P00533 |
Alternative identifier for interactor A | intact:EBI-916819 ensembl:ENSRNOP00000014309.2 ensembl:ENSRNOP00055005751 ensembl:ENSRNOP00060000740 ensembl:ENSRNOP00065016650 |
Alternative identifier for interactor B | intact:EBI-297353 intact:EBI-28985169 uniprotkb:Q9BZS2 uniprotkb:Q9GZX1 uniprotkb:Q9H2C9 uniprotkb:Q9H3C9 uniprotkb:Q9UMD7 uniprotkb:Q9UMD8 uniprotkb:Q9UMG5 uniprotkb:O00688 uniprotkb:O00732 uniprotkb:P06268 uniprotkb:Q14225 uniprotkb:Q92795 uniprotkb:Q68GS5 ensembl:ENSP00000275493.2 |
Aliases for A | psi-mi:ptn1_rat(display_long) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) uniprotkb:Ptpn1(gene name) psi-mi:Ptpn1(display_short) |
Aliases for B | psi-mi:egfr_human(display_long) uniprotkb:ERBB1(gene name synonym) uniprotkb:EGFR(gene name) psi-mi:EGFR(display_short) uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym) uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym) uniprotkb:ERBB(gene name synonym) uniprotkb:HER1(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
First author | Zhang et al. (1993) |
Identifier of the publication | mint:MINT-6732123 pubmed:7685104 doi:10.1073/pnas.90.10.4446 |
NCBI Taxonomy identifier for interactor A | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0217"(phosphorylation reaction) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-8605429 mint:MINT-6793256 |
Confidence score | intact-miscore:0.80 |
Complex expansion | - |
Biological role A | Enzyme |
Biological role B | Enzyme target |
Experimental role A | Neutral component |
Experimental role B | Neutral component |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:T2 comment:D\A Trapping mutant form of PTP1B comment:homomint comment:mint partial coverage:partial coverage |
NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
Parameters of the interaction | kcat:75.7x10(second) km:2.63x10^-6(molar) |
Creation date | 2008/10/23 |
Update date | 2014/10/16 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | phosphorylated residue:1016-1016(MINT-6800852) binding-associated region:1011-1021(MINT-6793267) |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Predetermined participant |
Participant identification method for interactor B | Peptide synthesis |