Curation Details
Interaction ID: MINT-6793235

Unique identifier for interactor Auniprotkb:P09619
Unique identifier for interactor Buniprotkb:P41499
Alternative identifier for interactor Aintact:EBI-641237
uniprotkb:B5A957
ensembl:ENSP00000261799.4
uniprotkb:Q8N5L4
Alternative identifier for interactor Bintact:EBI-7180604
uniprotkb:Q62626
intact:MINT-4591731
Aliases for Apsi-mi:pgfrb_human(display_long)
uniprotkb:CD140 antigen-like family member B(gene name synonym)
uniprotkb:PDGFRB(gene name)
psi-mi:PDGFRB(display_short)
uniprotkb:Beta-type platelet-derived growth factor receptor(gene name synonym)
uniprotkb:PDGFR(gene name synonym)
uniprotkb:Platelet-derived growth factor receptor 1(gene name synonym)
uniprotkb:Beta platelet-derived growth factor receptor(gene name synonym)
uniprotkb:PDGFR1(gene name synonym)
Aliases for Bpsi-mi:ptn11_rat(display_long)
uniprotkb:Ptpn11(gene name)
psi-mi:Ptpn11(display_short)
uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)
uniprotkb:SH-PTP2(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorKlinghoffer et al. (1995)
Identifier of the publicationmint:MINT-6672627
pubmed:7545675
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8581220
mint:MINT-6793235
Confidence scoreintact-miscore:0.59
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F3 F4 F5
comment:SHP2 dephosphorylate Y751;Y771,Y740
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/10/23
Update date2020/01/08
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:?-?(MINT-6793248)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by autoradiography
Participant identification method for interactor BPredetermined participant