Curation Details
Interaction ID: MINT-6765422

Unique identifier for interactor Auniprotkb:P18031
Unique identifier for interactor Buniprotkb:P97465
Alternative identifier for interactor Aintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Alternative identifier for interactor Bintact:EBI-914917
ensembl:ENSMUSP00000087079.6
uniprotkb:Q9R213
Aliases for Apsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Aliases for Bpsi-mi:dok1_mouse(display_long)
uniprotkb:Downstream of tyrosine kinase 1(gene name synonym)
uniprotkb:"p62(dok)"(gene name synonym)
uniprotkb:Dok1(gene name)
psi-mi:Dok1(display_short)
uniprotkb:Dok(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorMertins et al. (2008)
Identifier of the publicationpubmed:18515860
mint:MINT-6742313
doi:10.1074/mcp.M800196-MCP200
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7945309
mint:MINT-6765422
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:T3
comment:D\A Q\A Trapping mutant form of PTP1B. Hyperphosphorylaton in PTP1B-\- mouse.
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:1-321(MINT-6765425)
glutathione s tranferase tag:?-?(MINT-6765427)
Feature(s) for interactor Bphosphorylated residue:376-376(MINT-6765434)
phosphorylated residue:450-450(MINT-6765436)
phosphorylated residue:295-295(MINT-6765432)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BIdentification by mass spectrometry