Curation Details
Interaction ID: MINT-6764626

Unique identifier for interactor Auniprotkb:P18031
Unique identifier for interactor Buniprotkb:P56945
Alternative identifier for interactor Aintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Alternative identifier for interactor Bintact:EBI-702093
uniprotkb:B4DIW5
uniprotkb:F8WA69
uniprotkb:Q6QEF7
uniprotkb:B7Z7X7
uniprotkb:F5GXV6
uniprotkb:B3KWD7
uniprotkb:B4DEV4
uniprotkb:B4DGB5
uniprotkb:E9PCL5
uniprotkb:E9PCV2
uniprotkb:F5GXA2
uniprotkb:F5H7Z0
intact:EBI-10963425
ensembl:ENSP00000162330.5
Aliases for Apsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Aliases for Bpsi-mi:bcar1_human(display_long)
uniprotkb:CRK-associated substrate(gene name synonym)
uniprotkb:p130cas(gene name synonym)
uniprotkb:BCAR1(gene name)
psi-mi:BCAR1(display_short)
uniprotkb:CAS(gene name synonym)
uniprotkb:CRKAS(gene name synonym)
uniprotkb:CASS1(gene name synonym)
uniprotkb:Cas scaffolding protein family member 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0019"(coimmunoprecipitation)
First authorLiang et al. (2005)
Identifier of the publicationpubmed:15866871
mint:MINT-6671282
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7615682
mint:MINT-6764626
Confidence scoreintact-miscore:0.79
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:The trapping mutant D181A and D181A\Q262A do not activate the SRC kinase;the inactive SRC kinase does not phosphorilate p130CAS
figure legend:F6 f7
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:10090(mouse-l cells)
taxid:10090(Mus musculus embryo fibroblast, Moloney Sarcoma Virus transformed)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aha tag:?-?(MINT-6764657)
mutation disrupting interaction:309-309(MINT-6785559)
mutation disrupting interaction:310-310(MINT-6787842)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot