Curation Details
Interaction ID: MINT-6764613

Unique identifier for interactor Auniprotkb:P18031
Unique identifier for interactor Buniprotkb:P40763
Alternative identifier for interactor Aintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Alternative identifier for interactor Bintact:EBI-518675
uniprotkb:K7ENL3
ensembl:ENSP00000264657.4
ensembl:ENSP00000467985.1
ensembl:ENSP00000503102.1
ensembl:ENSP00000503181.1
ensembl:ENSP00000504184.1
uniprotkb:O14916
uniprotkb:Q9BW54
uniprotkb:A8K7B8
Aliases for Apsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Aliases for Bpsi-mi:stat3_human(display_long)
uniprotkb:Acute-phase response factor(gene name synonym)
uniprotkb:STAT3(gene name)
psi-mi:STAT3(display_short)
uniprotkb:APRF(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorLund et al. (2005)
Identifier of the publicationpubmed:15821101
mint:MINT-6673264
imex:IM-23288
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7582681
mint:MINT-6764613
imex:IM-23288-2
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 4b
comment:homomint
comment:mint
causality statement:P18031 is required for dephosphorylation of P40763
causality statement:P18031 decreases activity of P40763
dataset:Virus - Publications including interactions involving viral proteins
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
partial coverage:partial coverage
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/24
negative Boolean valuefalse
Feature(s) for interactor Asufficient binding region:1-321(MINT-6764616)
glutathione s tranferase tag:?-?
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BWestern blot