Curation Details
Interaction ID: MINT-6763884

Unique identifier for interactor Auniprotkb:P49023
Unique identifier for interactor Buniprotkb:O13016
Alternative identifier for interactor Aintact:EBI-702209
uniprotkb:O14970
uniprotkb:O14971
uniprotkb:O60360
uniprotkb:B2RAI3
uniprotkb:Q5HYA4
uniprotkb:B7ZMB4
ensembl:ENSP00000228307.7
Alternative identifier for interactor Bintact:EBI-6938259
uniprotkb:Q90704
intact:UNK-6008604
Aliases for Apsi-mi:paxi_human(display_long)
uniprotkb:PXN(gene name)
psi-mi:PXN(display_short)
Aliases for Bpsi-mi:ptn1_chick(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
uniprotkb:CPTP1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorTakino et al. (2003)
Identifier of the publicationpubmed:12799422
mint:MINT-6742308
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9031(chick)
taxid:9031("Gallus gallus (Chicken)")
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6938373
mint:MINT-6763884
Confidence scoreintact-miscore:0.49
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1
comment:The phosphatase overexpression cause the dephosphorylation of predicted substrate.
comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein.
comment:homomint
comment:domino
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293 ebna)
taxid:9606(Homo sapiens HEK293EBNA embryonic kidney cell)
Parameters of the interaction-
Creation date2008/09/18
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bgreen fluorescent protein tag:?-?(MINT-6763889)
binding-associated region:?-?(MINT-6763887)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot