Curation Details
Interaction ID: MINT-6763872

Unique identifier for interactor Auniprotkb:O13016
Unique identifier for interactor Buniprotkb:P56945
Alternative identifier for interactor Aintact:EBI-6938259
uniprotkb:Q90704
intact:UNK-6008604
Alternative identifier for interactor Bintact:EBI-702093
uniprotkb:B4DIW5
uniprotkb:F8WA69
uniprotkb:Q6QEF7
uniprotkb:B7Z7X7
uniprotkb:F5GXV6
uniprotkb:B3KWD7
uniprotkb:B4DEV4
uniprotkb:B4DGB5
uniprotkb:E9PCL5
uniprotkb:E9PCV2
uniprotkb:F5GXA2
uniprotkb:F5H7Z0
intact:EBI-10963425
ensembl:ENSP00000162330.5
Aliases for Apsi-mi:ptn1_chick(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
uniprotkb:CPTP1(gene name synonym)
Aliases for Bpsi-mi:bcar1_human(display_long)
uniprotkb:CRK-associated substrate(gene name synonym)
uniprotkb:p130cas(gene name synonym)
uniprotkb:BCAR1(gene name)
psi-mi:BCAR1(display_short)
uniprotkb:CAS(gene name synonym)
uniprotkb:CRKAS(gene name synonym)
uniprotkb:CASS1(gene name synonym)
uniprotkb:Cas scaffolding protein family member 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorTakino et al. (2003)
Identifier of the publicationpubmed:12799422
mint:MINT-6742308
NCBI Taxonomy identifier for interactor Ataxid:9031(chick)
taxid:9031("Gallus gallus (Chicken)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6938286
mint:MINT-6763872
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1
comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein.
comment:Dephosphorylation does not occur in cell overexpressing of CRKII.The phosphatase overexpression cause the dephosphorylation of predicted substrate.
comment:homomint
comment:domino
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293 ebna)
taxid:9606(Homo sapiens HEK293EBNA embryonic kidney cell)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:?-?(MINT-6763878)
green fluorescent protein tag:?-?(MINT-6763880)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot