Unique identifier for interactor A | uniprotkb:O60674 |
Unique identifier for interactor B | uniprotkb:P18031 |
Alternative identifier for interactor A | intact:EBI-518647 uniprotkb:O14636 uniprotkb:O75297 intact:EBI-28977715 ensembl:ENSP00000371067.4 |
Alternative identifier for interactor B | intact:EBI-968788 uniprotkb:Q5TGD8 uniprotkb:Q9BQV9 uniprotkb:Q9NQQ4 ensembl:ENSP00000360683.3 |
Aliases for A | psi-mi:jak2_human(display_long) uniprotkb:Janus kinase 2(gene name synonym) uniprotkb:JAK2(gene name) psi-mi:JAK2(display_short) |
Aliases for B | psi-mi:ptn1_human(display_long) uniprotkb:PTPN1(gene name) psi-mi:PTPN1(display_short) uniprotkb:PTP1B(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0096"(pull down) |
First author | Zabolotny et al. (2002) |
Identifier of the publication | pubmed:11970898 mint:MINT-6732089 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-8306100 mint:MINT-6763494 |
Confidence score | intact-miscore:0.82 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Prey |
Experimental role B | Bait |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:F1C comment:"\"This experiment uses phosphates mutants, so called trapping mutants, that still bind to their substrates but are not able to carry the phosphorylation reaction through. Development of \\"substrate-trapping\\" mutants to identify physiological substrates of protein tyrosine phosphatases. Flint AJ, Tiganis T, Barford D, Tonks NK. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1680-5. CS Trapping mutant form of PTP1B has been used.\"" comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins partial coverage:partial coverage |
NCBI Taxonomy identifier for the host organism | taxid:9606(human-293) taxid:9606(Homo sapiens HEK293 embryonic kidney cell) |
Parameters of the interaction | - |
Creation date | 2008/09/18 |
Update date | 2025/03/31 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | binding-associated region:?-?(MINT-6763499) glutathione s tranferase tag:?-?(MINT-6787204) |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Western blot |
Participant identification method for interactor B | Western blot |