| Unique identifier for interactor A | uniprotkb:P18031 |
| Unique identifier for interactor B | uniprotkb:P40763 |
| Alternative identifier for interactor A | intact:EBI-968788 uniprotkb:Q5TGD8 uniprotkb:Q9BQV9 uniprotkb:Q9NQQ4 ensembl:ENSP00000360683.3 |
| Alternative identifier for interactor B | intact:EBI-518675 uniprotkb:O14916 uniprotkb:Q9BW54 uniprotkb:A8K7B8 uniprotkb:K7ENL3 ensembl:ENSP00000264657.4 ensembl:ENSP00000467985.1 ensembl:ENSP00000503102.1 ensembl:ENSP00000503181.1 ensembl:ENSP00000504184.1 ensembl:ENSP00000520412.1 |
| Aliases for A | psi-mi:ptn1_human(display_long) uniprotkb:PTPN1(gene name) psi-mi:PTPN1(display_short) uniprotkb:PTP1B(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) |
| Aliases for B | psi-mi:stat3_human(display_long) uniprotkb:Acute-phase response factor(gene name synonym) uniprotkb:STAT3(gene name) psi-mi:STAT3(display_short) uniprotkb:APRF(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
| First author | Zabolotny et al. (2002) |
| Identifier of the publication | pubmed:11970898 mint:MINT-6732089 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8306046 mint:MINT-6763483 |
| Confidence score | intact-miscore:0.62 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F1A comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein. comment:The phosphatase overexpression causes the dephosphorylation of predicted substrate. comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_7) taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) |
| Parameters of the interaction | - |
| Creation date | 2008/09/18 |
| Update date | 2025/11/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:?-?(MINT-6763488) |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |