| Unique identifier for interactor A | uniprotkb:P18031 |
| Unique identifier for interactor B | uniprotkb:O60674 |
| Alternative identifier for interactor A | intact:EBI-968788 ensembl:ENSP00000360683.3 uniprotkb:Q5TGD8 uniprotkb:Q9BQV9 uniprotkb:Q9NQQ4 |
| Alternative identifier for interactor B | intact:EBI-518647 ensembl:ENSP00000371067.4 uniprotkb:O14636 uniprotkb:O75297 intact:EBI-28977715 |
| Aliases for A | psi-mi:ptn1_human(display_long) uniprotkb:PTPN1(gene name) psi-mi:PTPN1(display_short) uniprotkb:PTP1B(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) |
| Aliases for B | psi-mi:jak2_human(display_long) uniprotkb:Janus kinase 2(gene name synonym) uniprotkb:JAK2(gene name) psi-mi:JAK2(display_short) |
| Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
| First author | Zabolotny et al. (2002) |
| Identifier of the publication | pubmed:11970898 mint:MINT-6732089 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8306022 mint:MINT-6763472 |
| Confidence score | intact-miscore:0.82 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F1A comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein. comment:The phosphatase overexpression causes the dephosphorylation of predicted substrate. comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:9534(chlae-cos_7) taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) |
| Parameters of the interaction | - |
| Creation date | 2008/09/18 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:?-?(MINT-6763479) |
| Feature(s) for interactor B | phosphorylated residue:1007-1008(MINT-6763475) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |