Curation Details
Interaction ID: MINT-6762880

Unique identifier for interactor Auniprotkb:P35570
Unique identifier for interactor Buniprotkb:P27986
Alternative identifier for interactor Aintact:EBI-520230
Alternative identifier for interactor Bintact:EBI-79464
uniprotkb:D3DWA0
uniprotkb:B3KT19
uniprotkb:E7EX19
ensembl:ENSP00000428056.1
ensembl:ENSP00000429277.1
ensembl:ENSP00000513316.1
ensembl:ENSP00000513333.1
intact:EBI-28974553
uniprotkb:Q15747
uniprotkb:Q4VBZ7
uniprotkb:Q53EM6
uniprotkb:Q8IXA2
uniprotkb:Q8N1C5
Aliases for Apsi-mi:irs1_rat(display_long)
uniprotkb:pp185(gene name synonym)
uniprotkb:Irs1(gene name)
psi-mi:Irs1(display_short)
uniprotkb:Irs-1(gene name synonym)
Aliases for Bpsi-mi:p85a_human(display_long)
uniprotkb:PIK3R1(gene name)
psi-mi:PIK3R1(display_short)
uniprotkb:GRB1(gene name synonym)
uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)
Interaction detection methodspsi-mi:"MI:0047"(far western blotting)
First authorGoldstein et al. (2000)
Identifier of the publicationpubmed:10660596
mint:MINT-6671253
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7188272
mint:MINT-6762880
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4
comment:binding lost upon PTP1B,SHP2,PTPalpha,LAR dephosphorylation
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aphosphorylated residue:?-?(MINT-6762891)
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-6762886)
binding-associated region:333-428(MINT-6762883)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant