| Unique identifier for interactor A | uniprotkb:P35570 |
| Unique identifier for interactor B | uniprotkb:Q06124 |
| Alternative identifier for interactor A | intact:EBI-520230 |
| Alternative identifier for interactor B | intact:EBI-297779 uniprotkb:Q96HD7 uniprotkb:A8K1D9 ensembl:ENSP00000340944.3 intact:EBI-14351608 intact:EBI-11988773 intact:EBI-13004965 |
| Aliases for A | psi-mi:irs1_rat(display_long) uniprotkb:pp185(gene name synonym) uniprotkb:Irs1(gene name) psi-mi:Irs1(display_short) uniprotkb:Irs-1(gene name synonym) |
| Aliases for B | psi-mi:ptn11_human(display_long) uniprotkb:PTPN11(gene name) psi-mi:PTPN11(display_short) uniprotkb:PTP2C(gene name synonym) uniprotkb:SHPTP2(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym) uniprotkb:SH-PTP3(gene name synonym) uniprotkb:SH-PTP2(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
| First author | Goldstein et al. (2000) |
| Identifier of the publication | pubmed:10660596 mint:MINT-6671253 |
| NCBI Taxonomy identifier for interactor A | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7188050 mint:MINT-6762811 |
| Confidence score | intact-miscore:0.66 |
| Complex expansion | - |
| Biological role A | Enzyme target |
| Biological role B | Enzyme |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:PTP1B is the more active phosphatase toward IRS1 figure legend:F1;F2;F3 comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins partial coverage:partial coverage |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2008/09/18 |
| Update date | 2024/11/29 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | glutathione s tranferase tag:?-?(MINT-6762816) binding-associated region:?-?(MINT-6762814) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |