Curation Details
Interaction ID: MINT-6762786

Unique identifier for interactor Auniprotkb:P62993
Unique identifier for interactor Buniprotkb:P35570
Alternative identifier for interactor Aintact:EBI-401755
ensembl:ENSP00000339007.4
ensembl:ENSP00000376345.1
ensembl:ENSP00000376347.1
ensembl:ENSP00000496913.1
uniprotkb:P29354
uniprotkb:Q14450
uniprotkb:Q63057
uniprotkb:Q63059
Alternative identifier for interactor Bintact:EBI-520230
Aliases for Apsi-mi:grb2_human(display_long)
uniprotkb:GRB2(gene name)
psi-mi:GRB2(display_short)
uniprotkb:ASH(gene name synonym)
uniprotkb:Adapter protein GRB2(gene name synonym)
uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)
uniprotkb:Protein Ash(gene name synonym)
Aliases for Bpsi-mi:irs1_rat(display_long)
uniprotkb:pp185(gene name synonym)
uniprotkb:Irs1(gene name)
psi-mi:Irs1(display_short)
uniprotkb:Irs-1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0047"(far western blotting)
First authorGoldstein et al. (2000)
Identifier of the publicationpubmed:10660596
mint:MINT-6671253
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7188247
mint:MINT-6762786
Confidence scoreintact-miscore:0.74
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1;F4
comment:binding lost upon PTP1B dephosphorylation
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?(MINT-6762792)
binding-associated region:60-152(MINT-6762789)
Feature(s) for interactor Bphosphorylated residue:?-?(MINT-6762797)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant