| Unique identifier for interactor A | uniprotkb:P18031 |
| Unique identifier for interactor B | uniprotkb:P34152 |
| Alternative identifier for interactor A | intact:EBI-968788 uniprotkb:Q5TGD8 uniprotkb:Q9BQV9 uniprotkb:Q9NQQ4 ensembl:ENSP00000360683.3 |
| Alternative identifier for interactor B | intact:EBI-77070 uniprotkb:Q5DTH7 uniprotkb:Q8C513 uniprotkb:Q8CFH7 uniprotkb:Q8CHM2 uniprotkb:Q8K2S0 uniprotkb:Q9DAW3 intact:EBI-644981 uniprotkb:O08578 ensembl:ENSMUSP00000105663.3 |
| Aliases for A | psi-mi:ptn1_human(display_long) uniprotkb:PTPN1(gene name) psi-mi:PTPN1(display_short) uniprotkb:PTP1B(gene name synonym) uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) |
| Aliases for B | psi-mi:fak1_mouse(display_long) uniprotkb:Ptk2(gene name) psi-mi:Ptk2(display_short) uniprotkb:Fadk(gene name synonym) uniprotkb:Fak(gene name synonym) uniprotkb:Fak1(gene name synonym) uniprotkb:Kiaa4203(gene name synonym) uniprotkb:pp125FAK(gene name synonym) uniprotkb:Protein-tyrosine kinase 2(gene name synonym) uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym) uniprotkb:p125FAK(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0434"(phosphatase assay) |
| First author | Liu et al. (1998) |
| Identifier of the publication | mint:MINT-6671324 pubmed:9418872 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:10090(mouse) taxid:10090(Mus musculus) |
| Interaction types | psi-mi:"MI:0203"(dephosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8672408 mint:MINT-6762573 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F4 comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein. comment:The phosphatase overexpression causes the dephosphorylation of predicted substrate in v-crk trasfected cells. comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins |
| NCBI Taxonomy identifier for the host organism | taxid:10116(rat-3y1) taxid:10116(Rat embryonic fibroblast 3Y1 cells) |
| Parameters of the interaction | - |
| Creation date | 2008/09/18 |
| Update date | 2025/03/31 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:?-?(MINT-6762578) ha tag:?-?(MINT-6762583) mutation disrupting interaction:310-310(MINT-6787675) mutation disrupting interaction:309-309(MINT-6762580) |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Western blot |