Curation Details
Interaction ID: MINT-6762549

Unique identifier for interactor Auniprotkb:P18031
Unique identifier for interactor Buniprotkb:Q8VI36
Alternative identifier for interactor Aintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Alternative identifier for interactor Bintact:EBI-983394
uniprotkb:Q3TB62
uniprotkb:Q3TZQ6
uniprotkb:Q8VI37
Aliases for Apsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Aliases for Bpsi-mi:paxi_mouse(display_long)
uniprotkb:Pxn(gene name)
psi-mi:Pxn(display_short)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorLiu et al. (1998)
Identifier of the publicationmint:MINT-6671324
pubmed:9418872
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:10090(mouse)
taxid:10090(Mus musculus)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8672350
mint:MINT-6762549
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4
comment:No evidence for a direct de-phosphorylation is reported in this experiments. Anyway the curator was self confident to indicate this interaction as an evidence of a direct phosphatase effect on the indicated protein.
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:10116(rat-3y1)
taxid:10116(Rat embryonic fibroblast 3Y1 cells)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:310-310(MINT-6787655)
ha tag:?-?(MINT-6762559)
mutation disrupting interaction:309-309(MINT-6762556)
binding-associated region:?-?(MINT-6762554)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BWestern blot