Curation Details
Interaction ID: MINT-6762537

Unique identifier for interactor Auniprotkb:Q8VI36
Unique identifier for interactor Buniprotkb:P18031
Alternative identifier for interactor Aintact:EBI-983394
uniprotkb:Q3TB62
uniprotkb:Q3TZQ6
uniprotkb:Q8VI37
Alternative identifier for interactor Bintact:EBI-968788
ensembl:ENSP00000360683.3
uniprotkb:Q5TGD8
uniprotkb:Q9BQV9
uniprotkb:Q9NQQ4
Aliases for Apsi-mi:paxi_mouse(display_long)
uniprotkb:Pxn(gene name)
psi-mi:Pxn(display_short)
Aliases for Bpsi-mi:ptn1_human(display_long)
uniprotkb:PTPN1(gene name)
psi-mi:PTPN1(display_short)
uniprotkb:PTP1B(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorLiu et al. (1998)
Identifier of the publicationmint:MINT-6671324
pubmed:9418872
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8672308
mint:MINT-6762537
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4
comment:The phosphatase overexpression causes the dephosphorylation of predicted substrate in v-crk trasfected cells.
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
NCBI Taxonomy identifier for the host organismtaxid:10116(rat-3y1)
taxid:10116(Rat embryonic fibroblast 3Y1 cells)
Parameters of the interaction-
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bha tag:?-?(MINT-6762545)
mutation disrupting interaction:215-215(MINT-6762542)
binding-associated region:?-?(MINT-6762540)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BPredetermined participant