Curation Details
Interaction ID: MINT-6762105

Unique identifier for interactor Auniprotkb:P20417
Unique identifier for interactor Buniprotkb:P00533
Alternative identifier for interactor Aintact:EBI-916819
ensembl:ENSRNOP00055005751
ensembl:ENSRNOP00060000740
ensembl:ENSRNOP00065016650
ensembl:ENSRNOP00000014309.2
Alternative identifier for interactor Bintact:EBI-297353
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
Aliases for Apsi-mi:ptn1_rat(display_long)
uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)
uniprotkb:Ptpn1(gene name)
psi-mi:Ptpn1(display_short)
Aliases for Bpsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorZhang et al. (1996)
Identifier of the publicationmint:MINT-5220976
pubmed:8621392
NCBI Taxonomy identifier for interactor Ataxid:10116(rat)
taxid:10116("Rattus norvegicus (Rat)")
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8674812
mint:MINT-6762105
Confidence scoreintact-miscore:0.80
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2
comment:"\"1014 residue has been modified(p-benzoyl-Phe(Bpa))for crosslinlking studies.\""
comment:homomint
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkcat:69.3x10(second)
km:3.3x10^-6(molar)
Creation date2008/09/18
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?(MINT-6762117)
binding-associated region:?-?(MINT-6762115)
Feature(s) for interactor Bphosphorylated residue:1016-1016(MINT-6762110)
binding-associated region:1011-1022(MINT-6762108)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPeptide synthesis