Curation Details
Interaction ID: MINT-6539601

Unique identifier for interactor Auniprotkb:O43597
Unique identifier for interactor Buniprotkb:P22681
Alternative identifier for interactor Aintact:EBI-742487
uniprotkb:B2R9J9
ensembl:ENSP00000366306.1
ensembl:ENSP00000366308.3
uniprotkb:Q5T6Z7
Alternative identifier for interactor Bintact:EBI-518228
uniprotkb:A3KMP8
ensembl:ENSP00000264033.3
Aliases for Apsi-mi:spy2_human(display_long)
uniprotkb:SPRY2(gene name)
psi-mi:SPRY2(display_short)
Aliases for Bpsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Interaction detection methodspsi-mi:"MI:0065"(isothermal titration calorimetry)
First authorNg et al. (2008)
Identifier of the publicationpubmed:18273061
imex:IM-11554
mint:MINT-6538879
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7811648
mint:MINT-6539601
imex:IM-11554-26
Confidence scoreintact-miscore:0.86
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F5
kinetics:kd 0.32 micromolar
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/05/05
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:49-61(MINT-6539604)
Feature(s) for interactor Bbinding-associated region:25-351(MINT-6539608)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant