Curation Details
Interaction ID: MINT-6539448

Unique identifier for interactor Auniprotkb:P22681
Unique identifier for interactor Buniprotkb:O14492
Alternative identifier for interactor Aintact:EBI-518228
ensembl:ENSP00000264033.3
uniprotkb:A3KMP8
Alternative identifier for interactor Bintact:EBI-7507432
uniprotkb:A6ND74
intact:MINT-1498797
uniprotkb:A0A0A0MTI2
ensembl:ENSP00000401883.3
ensembl:ENSP00000440273.4
Aliases for Apsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Aliases for Bpsi-mi:sh2b2_human(display_long)
uniprotkb:APS(gene name synonym)
uniprotkb:SH2B2(gene name)
psi-mi:SH2B2(display_short)
uniprotkb:Adapter protein with pleckstrin homology and Src homology 2 domains(gene name synonym)
uniprotkb:SH2 and PH domain-containing adapter protein APS(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorNg et al. (2008)
Identifier of the publicationpubmed:18273061
imex:IM-11554
mint:MINT-6538879
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7811391
mint:MINT-6539448
imex:IM-11554-17
Confidence scoreintact-miscore:0.66
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4G
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2008/05/05
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Aha tag:?-?(MINT-6539453)
mutation decreasing interaction:274-274(MINT-6539451)
Feature(s) for interactor Bmyc tag:?-?(MINT-6539457)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot