| Unique identifier for interactor A | uniprotkb:O43597 | 
| Unique identifier for interactor B | uniprotkb:P22681 | 
| Alternative identifier for interactor A | intact:EBI-742487 uniprotkb:Q5T6Z7 uniprotkb:B2R9J9 ensembl:ENSP00000366306.1 ensembl:ENSP00000366308.3  | 
| Alternative identifier for interactor B | intact:EBI-518228 uniprotkb:A3KMP8 ensembl:ENSP00000264033.3  | 
| Aliases for A | psi-mi:spy2_human(display_long) uniprotkb:SPRY2(gene name) psi-mi:SPRY2(display_short)  | 
| Aliases for B | psi-mi:cbl_human(display_long) uniprotkb:Signal transduction protein CBL(gene name synonym) uniprotkb:Proto-oncogene c-Cbl(gene name synonym) uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym) uniprotkb:RING finger protein 55(gene name synonym) uniprotkb:CBL(gene name) psi-mi:CBL(display_short) uniprotkb:CBL2(gene name synonym) uniprotkb:RNF55(gene name synonym) uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)  | 
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) | 
| First author | Ng et al. (2008) | 
| Identifier of the publication | pubmed:18273061 imex:IM-11554 mint:MINT-6538879  | 
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens)  | 
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens)  | 
| Interaction types | psi-mi:"MI:0915"(physical association) | 
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) | 
| Interaction identifier(s) in the corresponding source database | intact:EBI-7810977 mint:MINT-6539063 imex:IM-11554-4  | 
| Confidence score | intact-miscore:0.86 | 
| Complex expansion | - | 
| Biological role A | Unspecified role | 
| Biological role B | Unspecified role | 
| Experimental role A | Bait | 
| Experimental role B | Prey | 
| Interactor type A | Protein | 
| Interactor type B | Protein | 
| Annotations for the interaction | figure legend:F4C comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins curation depth:imex curation full coverage:Only protein-protein interactions  | 
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-293t) taxid:9606(Homo sapiens HEK293T embryonic kidney cell)  | 
| Parameters of the interaction | - | 
| Creation date | 2008/05/05 | 
| Update date | 2025/08/11 | 
| negative Boolean value | false | 
| Feature(s) for interactor A | flag tag:?-?(MINT-6539068) | 
| Feature(s) for interactor B | mutation disrupting interaction:274-274(MINT-6539079) ha tag:?-?(MINT-6539075)  | 
| Stoichiometry for interactor A | - | 
| Stoichiometry for interactor B | - | 
| Participant identification method for interactor A | Anti tag western blot | 
| Participant identification method for interactor B | Anti tag western blot |