Curation Details
Interaction ID: MINT-6505246

Unique identifier for interactor Auniprotkb:Q9Y4K3
Unique identifier for interactor Buniprotkb:P78556
Alternative identifier for interactor Aintact:EBI-359276
uniprotkb:Q8NEH5
uniprotkb:A6NKI7
uniprotkb:A8KAB3
uniprotkb:D3DR16
ensembl:ENSP00000337853.5
ensembl:ENSP00000433623.1
Alternative identifier for interactor Bintact:EBI-3913209
uniprotkb:Q99664
uniprotkb:Q53S51
ensembl:ENSP00000351671.4
Aliases for Apsi-mi:traf6_human(display_long)
uniprotkb:TRAF6(gene name)
psi-mi:TRAF6(display_short)
uniprotkb:RNF85(gene name synonym)
uniprotkb:Interleukin-1 signal transducer(gene name synonym)
uniprotkb:RING finger protein 85(gene name synonym)
uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym)
Aliases for Bpsi-mi:ccl20_human(display_long)
uniprotkb:CCL20(gene name)
psi-mi:CCL20(display_short)
uniprotkb:LARC(gene name synonym)
uniprotkb:MIP3A(gene name synonym)
uniprotkb:SCYA20(gene name synonym)
uniprotkb:Beta-chemokine exodus-1(gene name synonym)
uniprotkb:CC chemokine LARC(gene name synonym)
uniprotkb:Liver and activation-regulated chemokine(gene name synonym)
uniprotkb:Macrophage inflammatory protein 3 alpha(gene name synonym)
uniprotkb:Small-inducible cytokine A20(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorIha et al. (2008)
Identifier of the publicationpubmed:18239685
imex:IM-11552
mint:MINT-6505046
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7794977
mint:MINT-6505246
imex:IM-11552-12
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:IL-1beta induces the binding of A20 to TRAF6, which is abolished by overexpression of TAX1BP1 UBZ*. TRAF6 and A20 do not bind each other in TAX1BP1 KO cells.
figure legend:f8e f8f
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2008/04/09
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Aflag tag:?-?(MINT-6505253)
Feature(s) for interactor Btag:?-?(MINT-6505249)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot