Curation Details
Interaction ID: MINT-6492303

Unique identifier for interactor Auniprotkb:Q9UHD2
Unique identifier for interactor Buniprotkb:Q96CV9
Alternative identifier for interactor Aintact:EBI-356402
intact:EBI-5773956
intact:EBI-1383470
uniprotkb:Q8IYV3
uniprotkb:Q9NUJ5
uniprotkb:A8K4S4
ensembl:ENSP00000329967.5
ensembl:ENSP00000498995.1
Alternative identifier for interactor Bintact:EBI-748974
uniprotkb:Q5T672
uniprotkb:Q5T673
uniprotkb:Q5T674
uniprotkb:Q5T675
uniprotkb:Q7LDL9
uniprotkb:Q8N562
uniprotkb:Q9UET9
uniprotkb:Q9UEV4
uniprotkb:Q9Y218
uniprotkb:B3KP00
uniprotkb:D3DRS4
uniprotkb:D3DRS8
ensembl:ENSP00000263036.3
ensembl:ENSP00000368021.3
ensembl:ENSP00000368022.3
ensembl:ENSP00000368032.2
Aliases for Apsi-mi:tbk1_human(display_long)
uniprotkb:TBK1(gene name)
psi-mi:TBK1(display_short)
uniprotkb:NAK(gene name synonym)
uniprotkb:TANK-binding kinase 1(gene name synonym)
uniprotkb:T2K(gene name synonym)
uniprotkb:NF-kappa-B-activating kinase(gene name synonym)
Aliases for Bpsi-mi:optn_human(display_long)
uniprotkb:HYPL(gene name synonym)
uniprotkb:Optic neuropathy-inducing protein(gene name synonym)
uniprotkb:E3-14.7K-interacting protein(gene name synonym)
uniprotkb:Huntingtin-interacting protein L(gene name synonym)
uniprotkb:Huntingtin yeast partner L(gene name synonym)
uniprotkb:NEMO-related protein(gene name synonym)
uniprotkb:Transcription factor IIIA-interacting protein(gene name synonym)
uniprotkb:OPTN(gene name)
psi-mi:OPTN(display_short)
uniprotkb:FIP2(gene name synonym)
uniprotkb:GLC1E(gene name synonym)
uniprotkb:NRP(gene name synonym)
uniprotkb:HIP7(gene name synonym)
uniprotkb:Huntingtin-interacting protein 7(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorMorton et al. (2008)
Identifier of the publicationpubmed:18307994
imex:IM-11543
mint:MINT-6492190
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7821337
mint:MINT-6492303
imex:IM-11543-1
Confidence scoreintact-miscore:0.93
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1A F2C
comment:homomint
comment:mint
dataset:Virus - Publications including interactions involving viral proteins
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293il1r)
taxid:9606(Homo sapiens HEK293IL1R embryonic kidney cell)
Parameters of the interaction-
Creation date2008/04/04
Update date2024/11/21
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?(MINT-6492312)
Feature(s) for interactor Bha tag:?-?(MINT-6492308)
mutation increasing interaction:50-50(MINT-6492316)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot