| Unique identifier for interactor A | uniprotkb:P01344 |
| Unique identifier for interactor B | uniprotkb:P11717 |
| Alternative identifier for interactor A | intact:EBI-7178764 uniprotkb:E3UN45 uniprotkb:Q14299 intact:MINT-6380943 uniprotkb:B7WP08 uniprotkb:Q9UC69 uniprotkb:Q1WM26 uniprotkb:Q9UC68 uniprotkb:B3KX48 uniprotkb:P78449 uniprotkb:C9JAF2 ensembl:ENSP00000370796.1 ensembl:ENSP00000370802.1 ensembl:ENSP00000402047.2 ensembl:ENSP00000414497.2 ensembl:ENSP00000511997.1 ensembl:ENSP00000511998.1 |
| Alternative identifier for interactor B | intact:EBI-1048580 uniprotkb:Q7Z7G9 uniprotkb:Q96PT5 ensembl:ENSP00000349437.1 |
| Aliases for A | psi-mi:igf2_human(display_long) uniprotkb:T3M-11-derived growth factor(gene name synonym) uniprotkb:PP1446(orf name) uniprotkb:IGF2(gene name) psi-mi:IGF2(display_short) uniprotkb:Somatomedin-A(gene name synonym) |
| Aliases for B | psi-mi:mpri_human(display_long) uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym) uniprotkb:Insulin-like growth factor II receptor(gene name synonym) uniprotkb:M6P/IGF2 receptor(gene name synonym) uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym) uniprotkb:IGF2R(gene name) psi-mi:IGF2R(display_short) uniprotkb:MPRI(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0107"(surface plasmon resonance) |
| First author | Brown et al. (2008) |
| Identifier of the publication | pubmed:18046459 imex:IM-11533 mint:MINT-6380932 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7706944 mint:MINT-6381798 imex:IM-11533-16 |
| Confidence score | intact-miscore:0.56 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F5 T2 comment:"\"KA(affinity constant)= 56.1 x 10^8/M Surface plasmon resonance to measure binding affinities was conducted by passing a serial dilution of IGF-II (32 2 nM) over biotinylated IGF2R fragments immobilised to streptavidin-coated sensor chips (Rmax of approx100 RU).\"" comment:homomint comment:mint curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2008/02/20 |
| Update date | 2024/09/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | binding-associated region:?-?(MINT-6381805) mutation decreasing interaction:1901-1942(MINT-6381803) mutation decreasing interaction:1544-1544(MINT-6381824) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |