| Unique identifier for interactor A | uniprotkb:Q13616 |
| Unique identifier for interactor B | uniprotkb:P61081 |
| Alternative identifier for interactor A | intact:EBI-359390 uniprotkb:O60719 uniprotkb:Q08AL6 uniprotkb:Q8IYW1 uniprotkb:D3DWG3 ensembl:ENSP00000326804.3 ensembl:ENSP00000387160.1 ensembl:ENSP00000473318.1 ensembl:ENSP00000499255.1 ensembl:ENSP00000499277.1 ensembl:ENSP00000499398.1 |
| Alternative identifier for interactor B | intact:EBI-1041660 uniprotkb:O76069 uniprotkb:Q8VC50 ensembl:ENSP00000253023.2 |
| Aliases for A | psi-mi:cul1_human(display_long) uniprotkb:CUL1(gene name) psi-mi:CUL1(display_short) |
| Aliases for B | psi-mi:ubc12_human(display_long) uniprotkb:UBE2M(gene name) psi-mi:UBE2M(display_short) uniprotkb:UBC12(gene name synonym) uniprotkb:Ubiquitin-conjugating enzyme E2 M(gene name synonym) uniprotkb:NEDD8 carrier protein(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0415"(enzymatic study) |
| First author | Kumar et al. (2007) |
| Identifier of the publication | pubmed:17914462 imex:IM-14019 mint:MINT-6175264 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0567"(neddylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7629112 mint:MINT-6175286 imex:IM-14019-1 |
| Confidence score | intact-miscore:0.79 |
| Complex expansion | - |
| Biological role A | Enzyme target |
| Biological role B | Enzyme |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F5A comment:"\"In vitro neddylation was carried out in the presence of H2O2 using purified Ubc12, a complex containing Roc1 and the C-terminal portion (residues 324 776) of Cul-1, and 32P-NEDD8.\"" comment:homomint comment:mint dataset:Virus - Publications including interactions involving viral proteins curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2008/02/07 |
| Update date | 2024/11/29 |
| negative Boolean value | false |
| Feature(s) for interactor A | binding-associated region:324-776(MINT-6175297) |
| Feature(s) for interactor B | tag:?-?(MINT-6175289) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |